Developmental and Reproductive Toxicity Evaluation
Developmental and reproductive toxicity evaluation can detect the toxic effects of drugs during the complete reproductive cycle. Our company employs talented and highly trained toxicologists focused on rare disease drug safety evaluation, and can provide you with high-quality developmental and reproductive toxicity evaluation services to help you identify potential risks in subsequent stages of rare disease therapy research and development.
What is Developmental Toxicity?
Developmental toxicity is the study of various developmental abnormalities and their mechanisms caused by exposure to exogenous physical and chemical factors in developing organisms from fertilized egg, pregnancy, and postnatal period until sexual maturity, and provides a basis for risk or safety evaluation of physical and chemical factors and preventive measures. The effects of developmental toxicity on embryonic development include growth retardation, functional defects, malformations, and death.
What is Reproductive Toxicity?
Reproductive toxicity is used to evaluate the effects of drugs on mammalian reproduction. It is closely related to toxicology studies such as acute toxicity, long-term toxicity, and genotoxicity, and is an important link for drugs to enter clinical research and marketing. In the process of drug development, the purpose of reproductive toxicity research is to reflect the effects of drugs on mammalian reproductive function and development through animal experiments and to predict the possible adverse effects on germ cells, conception, pregnancy, delivery, lactation, and other parental reproductive functions, as well as the adverse effects on offspring embryo-fetal development and postnatal development.
With a complete developmental and reproductive toxicity research laboratory and animal model platform, our company provides one-stop developmental and reproductive toxicity evaluation services including dose research, administration route design, animal species selection, toxicity analysis, etc.
Fertility and early embryo development (FEED) toxicity evaluation is the first segment of developmental and reproductive toxicology evaluation. Our company has many years of experience in FEED evaluation services and has the resources and capabilities to provide customers with custom study designs.
Embryo-fetal development (EFD) toxicity evaluation is the second segment of developmental and reproductive toxicology evaluation. Our company provides comprehensive services for embryo-fetal development toxicity evaluation to leading and emerging biopharmaceutical companies and scientific research institutions.
Perinatal toxicity evaluation is the third segment of developmental and reproductive toxicology evaluation. Our company employs talented and highly trained toxicologists focused on rare disease drug safety evaluation services, and can provide complete perinatal toxicity evaluation services to accelerate rare disease therapy research and development.
Why Choose Us?
With many years of experience and a proven track record of quality, innovation, and customer support, our company provides comprehensive developmental and reproductive toxicity evaluation services for rare disease therapy research and development. If you are interested in our services, please feel free to contact us for more information.
- Yang, C., et al. "Reproductive toxicity due to herbicide exposure in freshwater organisms." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 248 (2021): 109103.
For Research Use Only.