Drug Absorption Studies
Drug absorption refers to the process by which drugs enter the blood circulation from the site of administration. Our company provides high-quality data and rapid turnaround to support various rare disease drug development and preclinical research. We can perform complete drug absorption studies to evaluate rare disease drug candidates.
What are Drug Absorption Studies?
Drug absorption is defined as the transportation of unmetabolized drugs from the site of administration to the body's circulatory system. It is divided into gastrointestinal absorption and extra-gastrointestinal absorption. Drugs must cross several semi-permeable cell membranes before reaching the circulatory system. There are three mechanisms for drug absorption: passive transport, active transport, and other nonspecific drug transporters, which are closely related to the pharmacokinetic characteristics of the drug.
How are Drug Absorption Studies Performed?
In addition to direct intravenous administration, drug absorption is related to the drug's administration route, physiochemical properties, absorption environment, etc. Drug absorption can be studied through in vitro and in vivo experiments. In vitro, some special models can be used for studies. In vivo studies characterize the absorption characteristics of a drug by analyzing its concentration in plasma and are usually performed in rodents and non-rodent animals, and can be administered by various routes (e.g., oral, intravenous, subcutaneous, intramuscular, topical, sublingual, and ocular administration).
What Services Can We Provide?
A variety of animals from different species can be selected to cover various experimental animals required in preclinical drug development. Our company provides customers with high-quality drug absorption studies services for small molecule drugs, peptides, nucleosides, and nucleotides, as well as some biological macromolecule drugs. Our team will customize experimental designs for your project according to your specific requirements.
- Non-human Primates
- Single Agents
- Cassette Dosing
- Single Dose
- Repeat Dose
- Oral Drug Absorption
- Dermal Absorption
- Other Non-Oral Drug Absorption
The absorption of drugs is closely related to the permeability of cell membranes. Our company provides permeability study services to help customers comprehensively understand the absorption characteristics of drugs. In addition toin vivo drug absorption studies, we also provide in vitro models, such as Caco-2 cell line, to ensure that we can quickly respond to the changing needs of drug absorption study services.
Why Choose Us?
Our company employs talented and highly trained scientists focused on drug absorption studies for rare disease research. We have the capabilities and resources to provide professional communication and problem-solving support to ensure that we can quickly respond to the changing needs of your rare disease research projects. Please feel free to contact us for more information.
For Research Use Only.