Peptide Antibody Conjugation Service
Peptide antibody conjugation (PAC) has emerged as a powerful tool in biomedical research, offering the potential for targeted drug delivery, enhanced therapeutic efficacy, and improved diagnostics for rare diseases. Our company offers a full range of peptide antibody conjugation services, which can help you make progress in the development of rare disease peptide therapies.
Introduction to Peptide Antibody Conjugation
Peptide Antibody conjugation (PAC) represents a powerful and transformative approach to scientific research and the discovery of novel therapeutic interventions for rare diseases. By amalgamating the exquisite targeting specificity of antibodies with the potent therapeutic potential of peptides, PAC has unlocked unprecedented opportunities for targeted therapies across various disease indications, with a particular focus on cancer.
Fig.1 The peptide conjugation to the antibody via amine coupling (Kiyoshi, Masato, et al. 2023)
PAC has emerged as indispensable tools in the field of biomedical research, offering multifaceted advantages such as targeted drug delivery, augmented therapeutic effectiveness, and enhanced diagnostic capabilities. The convergence of antibodies and peptides within PAC has revolutionized the landscape of rare diseases, propelling the field toward personalized and more efficacious therapeutics strategies.
Our Services
Our company offers comprehensive a range of services for peptide antibody conjugation, ensuring the quality, stability, and efficacy of these conjugates. Through our state-of-the-art facilities and experienced team of scientists, we provide analytical techniques and assays to evaluate the properties and performance of PAC.
Peptide Design and Synthesis (Optional)
Through careful analysis of target antigens, we can engineer peptide sequences that possess optimal binding affinity and specificity.
Optional Gene Therapies
The success of PAC hinges upon the appropriate selection of antibodies with high binding affinity towards the target antigen. Our company offers a vast array of monoclonal and polyclonal antibodies for different applications.
Peptide Antibody Conjugation
We can provide cutting-edge conjugation methodologies, such as site-specific conjugation, to ensure a stable and homogeneous PAC product and preserve the native activity of the antibody and peptide.
Characterization of PAC
Comprehensive biochemical characterization includes:
- Conjugation efficiency
- Drug-to-antibody ratio (DAR)
- Stability
- The binding affinity of the PAC towards the target antigen
We are committed to providing biology experts with tailored PAC services to advance your research and rare disease drug development goals as efficiently and effectively as possible. If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Kiyoshi, Masato, et al. "Specific peptide conjugation to a therapeutic antibody leads to enhanced therapeutic potency and thermal stability by reduced Fc dynamics." Scientific Reports 13.1 (2023): 16561.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.