Anaemia

Anemia refers to a low number of red blood cells or a lower-than-normal hemoglobin concentration in the blood. The function of hemoglobin is to carry oxygen. If the number of red blood cells is too low or abnormal, or the concentration of hemoglobin is too low, the blood's ability to carry oxygen to body tissues is reduced, and symptoms such as fatigue, weakness, dizziness, and shortness of breath occur.

Anemia can also be classified according to the size of the red blood cells and the amount of hemoglobin in each red blood cell. If the red blood cells are smaller than normal, they are called microcytic anemia; if they are larger than normal, they are macrocytic anemia; if they are within the normal size range, they are normocytic anemia. The diagnostic criteria for anemia can be based on the hemoglobin or hematocrit (Hct) ratio.

Mechanisms of anaemia in anaemia of chronic disease ^[1].

Different Types of Anemia

There are several types of anemia, each with its own etiology. Anemia may be temporary or chronic, and its severity can range from mild to severe. In most cases, there is more than one cause of anemia.

• Aplastic Anemia
  Aplastic anemia is a condition that occurs when the body does not produce enough new blood cells. Patients can feel fatigued and are more prone to infections and uncontrolled bleeding.
• Thalassemia
  Thalassemia is an inherited blood disorder that causes the body to have less hemoglobin than normal. If you have a mild form of thalassemia, you may not need treatment. However, more severe cases may require regular blood transfusions.
• Iron Deficiency Anemia
  Iron deficiency anemia is caused by an iron deficiency. Without adequate amounts of iron, the body cannot produce enough hemoglobin in the red blood cells to transport oxygen. As a result, iron deficiency anemia may make you feel tired and short of breath.
• Sickle Cell Hemoglobin
  In sickle cell anemia, some red blood cells are shaped like a sickle or crescent. These sickle cells can also become stiff and sticky and may slow or block blood flow.

Anemia is a serious global public health problem that particularly affects young children and pregnant women. Therefore, an in-depth understanding of the underlying biology of the disease at the cellular and molecular levels is urgent. Protheragen has many years of research experience in the field of iron metabolism studies in cells and individuals and is committed to providing the broadest and highest quality tools for all types of anemia research. If you are interested in the services we offer, please contact us for more information.