Ferroptosis Analysis Service for Plants

During heat shock, plants undergo a cell death process similar to ferroptosis, but the exact mechanisms and networks remain poorly understood. Protheragen provides plant ferroptosis-related assays to help our clients conduct in-depth research on related topics.

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Plant Ferroptosis-like Cell Death

Ferroptosis is an iron-dependent, oxidative, non-apoptotic form of cell death that was originally described in mammalian cells. Recent studies have found that a cell death process similar to ferroptosis can be triggered by heat shock in Arabidopsis. Thus, ferroptosis may be a form of cell death that is conserved between animals and plants.

• Heat Stress Induced Ferroptosis-like Cell Death in Plants
  Extreme changes in temperature during the hot summer months can lead to plant cell death, resulting in severe agricultural losses. In studies on Arabidopsis, it was found that root hairs trigger cell death after heat shock treatment, but that this cell death process can be inhibited by pretreatment with the typical ferroptosis inhibitors Cpx and Fer-1. These results suggest that an ferroptosis-like form of cell death may be induced in Arabidopsis cells because of specific environmental stresses.

Ferroptosis processes in Arabidopsis root hair cells ^[1].

• Mechanism of Ferroptosis-like Cell Death in Plants
  Exposure of Arabidopsis root hair cells to heat shock (55°C) triggers cell death that is accompanied by ferroptosis features such as mitochondrial crinkling, cytoplasmic shrinkage, and lysogenic vesicles, and this cell death is accompanied by elevated iron and ROS but reduced glutathione levels, suggesting that this may be a cell death phenomenon like ferroptosis. Other studies have shown that the same cell death occurs when rice is infected by pathogenic bacteria.

Proposed Model of Iron- and ROS-Dependent Ferroptotic Cell Death ^[2].

Our Services

Plants show ferroptosis like that of mammals when subjected to external stresses. We offer a wide range of ferroptosis assays, including cell imaging, protein assays, and genetic assays, to help our clients conduct in-depth studies on the mechanisms of ferroptosis in plants.

• Iron Quantitative Assay
• ROS Detection
• Lipid Peroxide Assay
• Cell Structure Analysis
• Mitochondrial Membrane Potential Assay

We also provide cellular ferroptosis assays for plants under different stresses, and we provide ferroptosis study services for different model plants according to the requirements of our clients. We help our clients to conduct research on the mechanisms related to ferroptosis in plants through a comprehensive detection platform.

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Our Advantages

Protheragen has a professional team and advanced equipment, and the whole process is operated by experienced technicians to provide our customers with iron metabolism related cellular assay services. If you have any needs, please contact us.