Abiraterone (CB-7598)

Product Name:	Abiraterone (CB-7598)
CAT#:	DMME-2312-LGZ-1
Package:	5mg/10mg/50mg/100mg
Datasheet

Description

Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.

Basic Information

Synonyms:	CB-7598; CB7598
Application:	CYP17 Inhibitor
CAS Number:	154229-19-3
Formula:	C24H31NO
Molecular Weight:	349.2
SMILES:	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)O

Target Info

CYP17 (Cell-free assay):

2 nM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

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