Apigenin

Product Name:	Apigenin
CAT#:	DMME-2312-LGZ-7
Package:	50mg/100mg/200mg/10mM * 1mL in DMSO
Datasheet

Description

Apigenin is a natural product found in many plants that belongs to the flavonoid family and is the aglycone of several naturally occurring glycosides. Apigenin acts as a monoamine transport activator, one of the few chemicals that has been shown to have this property. Apigenin is a ligand of central benzodiazepine receptors and can competitively inhibit the binding of flunitrazepam with a Ki of 4 μM, exerting anxiolytic and mild sedative effects.

Basic Information

Synonyms:	4',5,7-trihydroxyflavone
Application:	Protein Kinase Inhibitor
CAS Number:	520-36-5
Formula:	C15H10O5
Molecular Weight:	270.2
SMILES:	C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
*Solubility-In vitro:*	DMSO: 46 mg/mL (170.22 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Target Info

CYP2C9:

2 μM(Ki)

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 37.01 mL 0.1 mM_5 mg: 185.05 mL 0.1 mM_10 mg: 370.1 mL 0.5 mM_1 mg: 7.4 mL 0.5 mM_5 mg: 37.01 mL 0.5 mM_10 mg: 74.02 mL 1 mM_1 mg: 3.7 mL 1 mM_5 mg: 18.5 mL 1 mM_10 mg: 37.01 mL 5 mM_1 mg: 0.74 mL 5 mM_5 mg: 3.7 mL 5 mM_10 mg: 7.4 mL

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