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Recombinant Human BRD4 Protein, N-10His-Flag

Product Name: Recombinant Human BRD4 Protein, N-10His-Flag
CAT#: DEERP-2402-LGZ-23


BRD4 is a chromatin reader protein that plays a crucial role in transcriptional regulation and epigenetic memory. It binds to acetylated histones, maintains high-order chromatin structure, and promotes phosphorylation of RNA Polymerase II. Inhibitors targeting BRD4 show promise as therapeutic molecules for various diseases including leukemias and breast cancer.

Basic Information

Synonyms: HUNK1, HUNK1bromodomain-containing protein 4, HUNKI, MCAP
Source/Host: E.coli
Tag: N-10His-Flag
Mol_Mass: 49 kDa
AP_Mol_Mass: 55-60 kDa
Uniprot: O60885
Accession: O60885
Sequence: Glu49-Glu460
Species: Human

Product Properties

Endotoxin Level: < 1.0 EU per μg (LAL method).
Formulation: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 200mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
Prior to lyophilization, add protectants including 5% - 8% trehalose, mannitol, and 0.01% Tween80.
Purity: > 95 % (by reducing SDS-PAGE).

Shipping and Handling

Shipping: Shipped at refrigerated temperatures (the product is a liquid).
Stability & Storage: Store the sample at a temperature below -20°C. It will remain stable for a period of 6 months. Please avoid subjecting it to repeated freeze-thaw cycles.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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