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Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein, N-His
| Product Name: |
Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein, N-His |
| CAT#: |
DEERP-2402-LGZ-18 |
| Datasheet |
|
Description
ADP-sugar Pyrophosphatase, also referred to as NUDT5, is tasked with eliminating harmful nucleotide derivatives from the cell and maintaining appropriate levels of crucial signaling nucleotides and their metabolites. NUDT5 operates similarly to a MutT-related protein by catalyzing the hydrolysis of 8-oxoGDP into 8-oxoGMP, thereby preventing the incorrect incorporation of 8-oxoGua into RNA molecules. Additionally, NUDT5 potentially plays significant roles in regulating the G1-S transition in mammalian cells. It possesses limited activity in hydrolyzing other nucleotide sugars as well.
Basic Information
| Synonyms: |
hYSAH1, YSA1, YSA1H, YSAH1 |
| Source/Host: |
E.coli |
| Tag: |
N-His |
| Mol_Mass: |
26.3 kDa |
| AP_Mol_Mass: |
35 kDa |
| Uniprot: |
Q9UKK9 |
| Accession: |
Q9UKK9 |
| Sequence: |
Glu2-Phe219 |
| Species: |
Human |
Product Properties
| Formulation: |
Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0
Prior to lyophilization, add protectants including 5% - 8% trehalose, mannitol, and 0.01% Tween80. |
| Purity: |
> 90 % (by reducing SDS-PAGE). |
Shipping and Handling
| Shipping: |
Shipped with ice packs (the product is lyophilized powder). |
| Stability & Storage: |
Please store lyophilized proteins at temperatures between -20 to -80°C for a maximum of 12 months. Once reconstituted, the protein solution can be stored at temperatures ranging from 4-8°C for a period of 2-7 days. If you need to store aliquots of reconstituted samples, please ensure they are kept below -20°C and they will remain stable for up to 3 months. |
All of our services and products are intended for
preclinical research use only and cannot be used to diagnose, treat or manage patients.
