GLUT

Glucose is the most basic energy source for living things, and metabolic homeostasis is tightly controlled through various mechanisms (such as hormonal regulation of insulin and glucagon). Glucose transporters (GLUTs) are a family of transmembrane proteins that regulate the entry of extracellular glucose into cells and are involved in processes such as glucose metabolism, inflammatory responses, and immune responses.

GLUT1 (SLC2A1) is a uniporter protein responsible for the facilitated transport of glucose across the plasma membranes of mammalian cells. GLUT2 (SLC2A2) is a transmembrane carrier protein that facilitates the movement of glucose across cell membranes. GLUT3 (SLC2A3), is predominantly expressed in the brain. GLUT4 (SLC2A4) is predominantly found in the heart, skeletal muscle, adipose tissue, and brain.

For more details about our glucose transporters, please click the links listed below.