WZB117

Product Name:	WZB117
CAT#:	DMG-2312-LGZ-2
Package:	10mg/25mg/50mg
Datasheet

Description

WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1), and inhibits cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells (IC50 = 10 uM).

Basic Information

Synonyms:	WZB 117; WZB-117
Application:	Glucose Transporter Inhibitor I
CAS Number:	1223397-11-2
Formula:	C20H13FO6
Molecular Weight:	368.31
SMILES:	C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O
*Solubility-In vitro:*	DMSO: 64 mg/mL (173.76 mM) Water: Insoluble Ethanol: 64 mg/mL (173.76 mM) * <1 mg/ml means slightly soluble or insoluble.

Target Info

GLUT1:

10μM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 27.15 mL 0.1 mM_5 mg: 135.76 mL 0.1 mM_10 mg: 271.51 mL 0.5 mM_1 mg: 5.43 mL 0.5 mM_5 mg: 27.15 mL 0.5 mM_10 mg: 54.3 mL 1 mM_1 mg: 2.72 mL 1 mM_5 mg: 13.58 mL 1 mM_10 mg: 27.15 mL 5 mM_1 mg: 0.54 mL 5 mM_5 mg: 2.72 mL 5 mM_10 mg: 5.43 mL

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