The CRISPRa (CRISPR activation) kit represents a unique iteration of CRISPR technology that doesn't alter or remove genes, but instead boosts or "activates" gene expression. This is achieved by using a dormant or "dead" variant of the Cas9 gene-slicing enzyme (dCas9), in addition to a molecule that triggers gene expression.
These tools can be adjusted by scientists to aim at practically any gene in the human genome's activation. The kits hold potential for research usage in areas such as analyses of gene function, discovery and verification of drug targets, genetic screening, assisted reproduction, and potential therapies.
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