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Protein Arginine Methyltransferases

Protein Arginine Methyltransferases

Arginine methylation of proteins is a ubiquitous post-translational modification in the cytoplasm and nucleus, involved in various cellular processes such as RNA processing, transcriptional regulation, signal transduction, DNA repair, etc., and is involved in regulating protein-protein interactions. There are three types of arginine methylation in eukaryotes: monomethylated arginine (MMA), asymmetric dimethylated arginine (aDMA), and symmetric dimethylated arginine (sDMA).

Protein arginine methyltransferases (PRMTs) are common enzymes in mammals and are responsible for methylating arginine in protein substrates. Abnormal expression of PRMTs is closely related to tumors, viral infections, cardiovascular system diseases, etc.

For more details about our protein arginine methyltransferases, please click the links listed below.

  • MS049
  • CAT#:

    DEPAM-2312-LGZ-1

  • Application:

    Dual Inhibitor of PRMT4 and PRMT6

  • CAS Number:

    1502816-23-0

  • MS023
  • CAT#:

    DEPAM-2312-LGZ-2

  • Application:

    PRMT1 Inhibitor

  • CAS Number:

    1831110-54-3

  • C7280948
  • CAT#:

    DEPAM-2312-LGZ-3

  • Application:

    PRMT1 Inhibitor

  • CAS Number:

    587850-67-7

  • GSK591
  • CAT#:

    DEPAM-2312-LGZ-4

  • Application:

    PRMT5 Inhibitor

  • CAS Number:

    1616391-87-7

  • SGC 707
  • CAT#:

    DEPAM-2312-LGZ-5

  • Application:

    PRMT3 Inhibitor

  • CAS Number:

    1687736-54-4

  • XY1
  • CAT#:

    DEPAM-2312-LGZ-6

  • Application:

    PRMT3 Inhibitor

  • CAS Number:

    1624117-53-8

  • HLCL-61
  • CAT#:

    DEPAM-2312-LGZ-7

  • Application:

    PRMT5 Inhibitor

  • CAS Number:

    1158279-20-9

  • AMI-1
  • CAT#:

    DEPAM-2312-LGZ-8

  • Application:

    Hmt1p/PRMT1 Inhibitor

  • CAS Number:

    20324-87-2

  • AMI5
  • CAT#:

    DEPAM-2312-LGZ-9

  • Application:

    Protein Methyltransferase Inhibitor

  • CAS Number:

    17372-87-1

  • EPZ020411
  • CAT#:

    DEPAM-2312-LGZ-10

  • Application:

    PRMT6 Inhibitor

  • CAS Number:

    1700663-41-7

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