MS023

Product Name:	MS023
CAT#:	DEPAM-2312-LGZ-2
Package:	5mg/10mg/25mg
Datasheet

Description

MS023 is a highly effective inhibitor of PRMTs 1, 3, 4, 6, and 8 with IC50s of 30, 119, 83, 8, and 8 nM, respectively, leading to asymmetric dimethylation of arginine residues.

Basic Information

Synonyms:	MS-023; MS 023
Application:	PRMT1 Inhibitor
CAS Number:	1831110-54-3
Formula:	C17H25N3O
Molecular Weight:	287.4
SMILES:	NCCN(C)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2
*Solubility-In vitro:*	DMSO: 50 mg/mL (173.96 mM) Water: Insoluble Ethanol: 50 mg/mL (173.96 mM) * <1 mg/ml means slightly soluble or insoluble.

Target Info

PRMT6:	4 nM
PRMT8:	5 nM
PRMT1:	30 nM
PRMT4:	83 nM
PRMT3:	119 nM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 34.79 mL 0.1 mM_5 mg: 173.97 mL 0.1 mM_10 mg: 347.95 mL 0.5 mM_1 mg: 6.96 mL 0.5 mM_5 mg: 34.79 mL 0.5 mM_10 mg: 69.59 mL 1 mM_1 mg: 3.48 mL 1 mM_5 mg: 17.4 mL 1 mM_10 mg: 34.79 mL 5 mM_1 mg: 0.7 mL 5 mM_5 mg: 3.48 mL 5 mM_10 mg: 6.96 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.