EPZ020411

Product Name:	EPZ020411
CAT#:	DEPAM-2312-LGZ-10
Package:	5mg/10mg/50mg
Datasheet

Description

EPZ020411 is a highly efficient and selective inhibitor of PRMT6, with an IC50 value of 10 nM and greater than 10-fold selectivity for PRMT1 and PRMT8.

Basic Information

Synonyms:	EPZ-020411
Application:	PRMT6 Inhibitor
CAS Number:	1700663-41-7
Formula:	C25H38N4O3
Molecular Weight:	442.59
SMILES:	CN(CC1=CNN=C1C2=CC=C(O[C@@H]3C[C@@H](OCCC4CCOCC4)C3)C=C2)CCNC

Target Info

PRMT6:	0.01 μM (IC50)
PRMT1:	0.119 μM (IC50)
PRMT8:	0.223 μM (IC50)

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

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