HLCL-61

Product Name:	HLCL-61
CAT#:	DEPAM-2312-LGZ-7
Package:	5mg/10mg/25mg
Datasheet

Description

HLCL-61 hydrochloride is a highly effective and selective PRMT5 inhibitor, it can be used to the treatment of acute myeloid leukemia.

Basic Information

Synonyms:	HLCL-61 hydrochloride
Application:	PRMT5 Inhibitor
CAS Number:	1158279-20-9
Formula:	C23H24N2O.HCl
Molecular Weight:	380.91
SMILES:	COC1=CC=CC=C1CNCC2=CC3=C(C=C2)N(CC)C4=C3C=CC=C4.[H]Cl
*Solubility-In vitro:*	DMSO: 65 mg/mL (170.64 mM) Water: Insoluble Ethanol: 65 mg/mL (170.64 mM) * <1 mg/ml means slightly soluble or insoluble.

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 26.25 mL 0.1 mM_5 mg: 131.26 mL 0.1 mM_10 mg: 262.53 mL 0.5 mM_1 mg: 5.25 mL 0.5 mM_5 mg: 26.25 mL 0.5 mM_10 mg: 52.51 mL 1 mM_1 mg: 2.63 mL 1 mM_5 mg: 13.13 mL 1 mM_10 mg: 26.25 mL 5 mM_1 mg: 0.53 mL 5 mM_5 mg: 2.63 mL 5 mM_10 mg: 5.25 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.