3-Aminobenzamide

Product Name:	3-Aminobenzamide
CAT#:	DEPA-2312-LGZ-7
Package:	10mM * 1mL in DMSO/250mg
Datasheet

Description

3-Aminobenzamide is a new type of PARP inhibitor that can increase the sensitivity of cells to radiation by inhibiting DNA damage repair in vitro.

Basic Information

Synonyms:	3-Aminobenzamide; 3-AB
Application:	PARP Inhibitor
CAS Number:	3544-24-9
Formula:	C7H8N2O
Molecular Weight:	136.2
SMILES:	C1=CC(=CC(=C1)N)C(=O)N
*Solubility-In vitro:*	In vitro (25°C): DMSO: 26 mg/mL (190.97 mM) Water: Insoluble Ethanol: 26 mg/mL
*Solubility-In vivo:*	30% propylene glycol, 5% Tween 80, 65% D5W: 28 mg/mL

Target Info

PARP:

<50 nM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 73.42 mL 0.1 mM_5 mg: 367.11 mL 0.1 mM_10 mg: 734.21 mL 0.5 mM_1 mg: 14.68 mL 0.5 mM_5 mg: 73.42 mL 0.5 mM_10 mg: 146.84 mL 1 mM_1 mg: 7.34 mL 1 mM_5 mg: 36.71 mL 1 mM_10 mg: 73.42 mL 5 mM_1 mg: 1.47 mL 5 mM_5 mg: 7.34 mL 5 mM_10 mg: 14.68 mL

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