Online Inquiry
Inquiry
5-Carboxylcytosine (5-caC) DNA Matched Antibody Pair
Description
5-Carboxylcytosine (5-caC) is a recently discovered DNA modification. Similar to the generation of 5-hydroxymethylcytosine (5-hmC) through the action of the Tet family of cytosine oxygenase enzymes on 5-methylcytosine (5-mC), it has been observed that the continued activity of Tet proteins on hydroxymethylcytosine leads to the generation of 5-formylcytosine (5-fC) and 5-carboxylcytosine. This conversion process is believed to be a potential pathway for DNA demethylation.
Basic Information
| Synonyms: | 5-caC |
| Application: | Quantitative ELISA |
| Assay Type: | Sandwich |
| Crossreactivity: | All |
| Detection Type: | Colorimetric |
| Kit Contains: | 1) Capture Antibody: Anti-5-Carboxylcytosine (5-caC) Rabbit Monoclonal Antibody, Clone RM462, 50 ug at 1.0 mg/mL in 50% Glycerol/PBS with 0.09% sodium azide, without BSA or other carrier proteins. 2) Detection Antibody: Biotin Anti-Adenine and Guanine Rabbit Monoclonal Antibody, Clone RM476, 25 ug at 1.0 mg/mL in 50% Glycerol/PBS with 0.09% sodium azide and 1% BSA |
| Quantity: | ELISA:Capture Antibody 50ng/well – 200ng/wellDetection Antibody 0.1ug/mL – 0.5ug/mL |
Shipping and Handling
| Storage (Long Term): | -20°C |
| Shipping: | Blue Ice |
| Handling Advice: | To prevent freeze/thaw cycles, it is recommended to prepare aliquots of the compound. |
| Stability: | When stored at a temperature of -20°C, it remains stable for at least 1 year after receipt. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
