ABT-888 (Veliparib)

Product Name:	ABT-888 (Veliparib)
CAT#:	DEPA-2312-LGZ-2
Package:	10mg/50mg/100mg/200mg/10mM * 1mL in DMSO
Datasheet

Description

ABT-888(Veliparib) is a highly effectiveial anti-cancer drug.

Basic Information

Synonyms:	ABT888
Application:	PARP Inhibitor
CAS Number:	912444-00-9
Formula:	C13H16N4O
Molecular Weight:	244.3
SMILES:	O=C(C1=C2NC([C@@]3(NCCC3)C)=NC2=CC=C1)N
*Solubility-In vitro:*	In vitro (25°C): DMSO: 17 mg/mL (69.58 mM) Water: Insoluble Ethanol: Insoluble
*Solubility-In vivo:*	0.5% methylcellulose+0.2% Tween 80: 4 mg/mL

Target Info

PARP-2:	2.9 nM (Ki)
PARP-1:	5.2 nM (Ki)

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 40.93 mL 0.1 mM_5 mg: 204.67 mL 0.1 mM_10 mg: 409.33 mL 0.5 mM_1 mg: 8.19 mL 0.5 mM_5 mg: 40.93 mL 0.5 mM_10 mg: 81.87 mL 1 mM_1 mg: 4.09 mL 1 mM_5 mg: 20.47 mL 1 mM_10 mg: 40.93 mL 5 mM_1 mg: 0.82 mL 5 mM_5 mg: 4.09 mL 5 mM_10 mg: 8.19 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.