AHR Antagonist 1

Product Name:	AHR Antagonist 1
CAT#:	DMAR-2312-LGZ-10
Package:	5mg/10mg/50mg/100mg
Datasheet

Description

AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2017202816A1 (Example 23). It has an IC50 of 39.9 nM in human cell lines.

Basic Information

Application:	AHR AntAgonist
CAS Number:	2162982-11-6
Formula:	C20H17ClFN3O3
Molecular Weight:	401.82
SMILES:	O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CC=CC(F)=C3)C1=O)N[C@@H](C)CO
*Solubility-In vitro:*	DMSO: 76 mg/mL (189.14 mM) Water: Insoluble Ethanol: 19 mg/mL (47.28 mM) * <1 mg/ml means slightly soluble or insoluble.

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 24.89 mL 0.1 mM_5 mg: 124.43 mL 0.1 mM_10 mg: 248.87 mL 0.5 mM_1 mg: 4.98 mL 0.5 mM_5 mg: 24.89 mL 0.5 mM_10 mg: 49.77 mL 1 mM_1 mg: 2.49 mL 1 mM_5 mg: 12.44 mL 1 mM_10 mg: 24.89 mL 5 mM_1 mg: 0.5 mL 5 mM_5 mg: 2.49 mL 5 mM_10 mg: 4.98 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.