AK-7

Product Name:	AK-7
CAT#:	DES-2312-LGZ-9
Package:	10mg/25mg/50mg/100mg
Datasheet

Description

AK-7 is a cell and brain permeability inhibitor of SIRT2 with an IC50 value of 15.5 μM.

Basic Information

Synonyms:	AK7
Application:	SIRT2 Inhibitor
CAS Number:	420831-40-9
Formula:	C19H21BrN2O3S
Molecular Weight:	437.35
SMILES:	C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NC3=CC(=CC=C3)Br
*Solubility-In vitro:*	DMSO: 77 mg/mL (176.06 mM) Water: Insoluble Ethanol: 3 mg/mL (6.85 mM) * <1 mg/ml means slightly soluble or insoluble.

Target Info

SIRT2:

15.5 μM (IC50)

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 22.86 mL 0.1 mM_5 mg: 114.32 mL 0.1 mM_10 mg: 228.65 mL 0.5 mM_1 mg: 4.57 mL 0.5 mM_5 mg: 22.86 mL 0.5 mM_10 mg: 45.73 mL 1 mM_1 mg: 2.29 mL 1 mM_5 mg: 11.43 mL 1 mM_10 mg: 22.86 mL 5 mM_1 mg: 0.46 mL 5 mM_5 mg: 2.29 mL 5 mM_10 mg: 4.57 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.