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Angiocidin (Human), ≥95% (SDS-PAGE)
Description
Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and α2β1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers.
Basic Information
Molecular Weight: | ~50kDa (SDS-PAGE) |
Synonyms: | PSMD4; 26S Proteasome Regulatory Subunit S5A; Rpn10; Multiubiquitin Chain-binding Protein; Antisecretory Factor 1; 26S Proteasome Non-ATPase Regulatory Subunit 4 |
Concentration: | 0.1mg/ml after reconstitution. |
Crossreactivity: | Human |
Endotoxin Content: | <0.1EU/μg |
Formulation: | Lyophilized. Contains PBS. |
Purity: | ≥95% (SDS-PAGE) |
Sequence: | Human angiocidin (aa 2-377) is untagged. |
Source/Host: | E. coli |
Shipping and Handling
Storage (Short Term): | 4°C |
Storage (Long Term): | -20°C |
Shipping: | Blue Ice |
Handling Advice: | Upon reconstitution, it is advisable to prepare aliquots of the compound and store them at a temperature of -20°C. To prevent freeze/thaw cycles, it is recommended to prepare aliquots of the compound. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0. 1% BSA should be used for further dilutions. |
Stability: | When stored at a temperature of -20°C, it remains stable for at least 6 months. Working aliquots are stable for up to 3 months when stored at -20°C. |
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