ANGPTL6 (Human) ELISA Kit
Description
Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose and energy metabolism. The serum levels of ANGPTL6 are significantly increased in obese humans, patients with type 2 diabetes mellitus (T2DM) and in metabolic syndrome. Therefore, ANGPTL6 may be a novel biomarker for metabolic diseases and may provide a novel therapeutic approach to counteract obesity, T2DM and insulin resistance.
Basic Information
| Synonyms: | Angiopoietin-like Protein 6; AGF; Angiopoietin-related Growth Factor |
| Application: | Quantitative ELISA |
| Assay Type: | Sandwich |
| Crossreactivity: | Human |
| Detection Type: | Colorimetric |
| Quantity: | 1 x 96 wells |
| Range: | 1.56 to 100 ng/ml |
| Sample Type: | Cell Culture Supernatant; Plasma; Serum |
| Sensitivity: | 1.2 ng/ml |
Shipping and Handling
| Storage (Short Term): | 4°C |
| Storage (Long Term): | 4°C |
| Shipping: | Blue Ice |
| Handling Advice: | After standard reconstitution, prepare aliquots and store at -20°C. To prevent freeze/thaw cycles, it is recommended to prepare aliquots of the compound. Plate and reagents should reach room temperature before use. |
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