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Anti-4-Hydroxy-2-Hexenal [4-HHE] (KKE53), mAB, Human
Description
4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts.
Basic Information
Application: | Immunohistochemistry: Recommended concentration is 0.5-1μg/mL on paraffin sections. |
Clone: | KKE53 |
Crossreactivity: | All; Human |
Formulation: | Frozen liquid. Contains 10mM PBS, 0.5% BSA and 0.1% NaN3. |
Immunogen/Antigen: | HHE-modified keyhole-lympet hemocyanine. |
Isotype: | Mouse IgG1κ |
Isotype Negative Control: | Mouse IgG1 Isotype Control |
Purity Detail: | Protein A purified. |
Source/Host: | Ascites |
Shipping and Handling
Storage (Short Term): | 4°C |
Storage (Long Term): | -20°C |
Shipping: | Blue Ice |
Handling Advice: | To prevent freeze/thaw cycles, it is recommended to prepare aliquots of the compound. |
Stability: | When stored at a temperature of -20°C, it remains stable for at least 3 years. |
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