Online Inquiry
Inquiry
ASC 1 (Q15650) Polyclonal Antibody
Description
Activate signal co-integrator-1 (ASC-1), also known as TRIP4, is a protein that enhances the activity of nuclear receptors involved in gene transcription. ASC-1 interacts with specific components of the RNA polymerase II complex and binds to basal transcription factors TBP and TFIIA. It works together with transcription integrators SRC-1 and CBP/p300 through its zinc finger motif, relying on their ligand-dependent transactivation domain AF2. In HeLa cells, ASC-1 is primarily located within the nucleus. However, during serum starvation conditions, it moves to the cytoplasm.
Basic Information
| Synonyms: | Activating signal cointegrator 1, ASC 1, ASC-1, HsT17391, Thyroid hormone receptor interactor 4, Thyroid receptor interacting protein 4, Thyroid receptor-interacting protein 4, TR-interacting protein 4, TRIP 4, TRIP-4, Trip4, TRIP4, ZC2HC5, Zinc finger C2HC5 type |
| Application: | IHC/ELISA |
| Label/Conjugates: | Unconjugated |
| Crossreactivity: | Human, Mouse |
| Source/Host: | Rabbit |
| Uniprot: | Q15650 |
| Accession: | BC012448 |
| Buffer: | 50% glycerol, PBS with 0.05% sodium azide, PH7.4 |
| Concentration: | 0.5 mg/mL |
| Isotype: | IgG |
| Purification: | Affinity purification |
Immunogen Properties
| Abbre: | TRIP4 |
| Clonality: | Polyclonal |
| Immunogen: | Recombinant protein derived from human TRIP4 |
Shipping and Handling
| Stability & Storage: | Store the sample at a temperature of -20°C and avoid subjecting it to repeated freeze/thaw cycles. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
