Azacitidine (Vidaza)

Product Name:	Azacitidine (Vidaza)
CAT#:	DEDM-2312-LGZ-1
Package:	100mg/10mM * 1mL in DMSO
Datasheet

Description

Azacitidine is a chemical analogue of cytosine nucleoside, which is used in DNA and RNA and mainly used in myelodysplastic syndrome (MDS).

Basic Information

Synonyms:	5-azacytidine; Mylosar; Ladakamycin; Vidaza
Application:	DNMT Inhibitor
CAS Number:	320-67-2
Formula:	C8H12N4O5
Molecular Weight:	244.2
SMILES:	C1=NC(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N
*Solubility-In vitro:*	In vitro (25°C): DMSO: Warmed: 45 mg/mL (184.28 mM) Water: Insoluble Ethanol: Insoluble
*Solubility-In vivo:*	5% DMSO+30% PEG 300+ddH2O: 9 mg/mL

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 40.95 mL 0.1 mM_5 mg: 204.75 mL 0.1 mM_10 mg: 409.5 mL 0.5 mM_1 mg: 8.19 mL 0.5 mM_5 mg: 40.95 mL 0.5 mM_10 mg: 81.9 mL 1 mM_1 mg: 4.1 mL 1 mM_5 mg: 20.48 mL 1 mM_10 mg: 40.95 mL 5 mM_1 mg: 0.82 mL 5 mM_5 mg: 4.1 mL 5 mM_10 mg: 8.19 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.