BMN673

Product Name:	BMN673
CAT#:	DEPA-2312-LGZ-9
Package:	5mg/10mg/25mg/50mg/10mM * 1mL in DMSO
Datasheet

Description

BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP), and has potential antineoplastic activity.

Basic Information

Synonyms:	BMN-673; BMN 673
Application:	PARP Inhibitor
CAS Number:	1207456-01-6
Formula:	C19H14F2N6O
Molecular Weight:	380.35
SMILES:	CN1C(=NC=N1)[C@@H]2[C@H](N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F
*Solubility-In vitro:*	DMSO: Warmed: 38 mg/mL (99.9 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Target Info

PARP (Cell-free assay):

0.58 nM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 26.29 mL 0.1 mM_5 mg: 131.46 mL 0.1 mM_10 mg: 262.92 mL 0.5 mM_1 mg: 5.26 mL 0.5 mM_5 mg: 26.29 mL 0.5 mM_10 mg: 52.58 mL 1 mM_1 mg: 2.63 mL 1 mM_5 mg: 13.15 mL 1 mM_10 mg: 26.29 mL 5 mM_1 mg: 0.53 mL 5 mM_5 mg: 2.63 mL 5 mM_10 mg: 5.26 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.