Calcifediol

Product Name:	Calcifediol
CAT#:	DMV-2312-LGZ-3
Package:	5mg/10mg/25mg/50mg/10mM * 1mL in DMSO
Datasheet

Description

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA, its ED50 value is 2 nM.

Basic Information

Synonyms:	25-Hydroxyvitamin D3; Calcidiol
CAS Number:	19356-17-3
Formula:	C27H44O2
Molecular Weight:	400.64
SMILES:	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C
*Solubility-In vitro:*	In vitro (25°C): DMSO: 74 mg/mL (184.7 mM) Water: Insoluble Ethanol: 18 mg/mL (44.93 mM)
*Solubility-In vivo:*	2% DMSO+30% PEG 300+5% Tween+ddH2O: 4 mg/mL

Target Info

Human Endogenous Metabolite

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg:	24.96 mL
0.1 mM_5 mg:	124.8 mL
0.1 mM_10 mg:	249.6 mL
0.5 mM_1 mg:	4.99 mL
0.5 mM_5 mg:	24.96 mL
0.5 mM_10 mg:	49.92 mL
1 mM_1 mg:	2.5 mL
1 mM_5 mg:	12.48 mL
1 mM_10 mg:	24.96 mL
5 mM_1 mg:	0.5 mL
5 mM_5 mg:	2.5 mL
5 mM_10 mg:	4.99 mL

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