Cambinol

Product Name:	Cambinol
CAT#:	DES-2312-LGZ-7
Package:	5mg/10mg/50mg/100mg
Datasheet

Description

Cambinol is a SIRT1 and SIRT2 inhibitor. IC50 values were 56 and 59 μM respectively.

Basic Information

Application:	SIRT1/SIRT2 Inhibitor
CAS Number:	14513-15-6
Formula:	C21H16N2O2S
Molecular Weight:	360.43
SMILES:	O=C(C(CC1=C2C=CC=CC2=CC=C1O)=C(C3=CC=CC=C3)N4)NC4=S
*Solubility-In vitro:*	DMSO: 19 mg/mL (52.71 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Target Info

SIRT1:	56 μM (IC50)
SIRT2:	59 μM (IC50)

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 27.74 mL 0.1 mM_5 mg: 138.72 mL 0.1 mM_10 mg: 277.45 mL 0.5 mM_1 mg: 5.55 mL 0.5 mM_5 mg: 27.74 mL 0.5 mM_10 mg: 55.49 mL 1 mM_1 mg: 2.77 mL 1 mM_5 mg: 13.87 mL 1 mM_10 mg: 27.74 mL 5 mM_1 mg: 0.55 mL 5 mM_5 mg: 2.77 mL 5 mM_10 mg: 5.55 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.