Decitabine

Product Name:	Decitabine
CAT#:	DMA-2312-LGZ-6
Package:	10mg/25mg/50mg/100mg/10mM * 1mL in DMSO
Datasheet

Description

Decitabine is a hypomethylating agent that inhibits DNA methyltransferase and causes DNA hypomethylation.

Basic Information

Synonyms:	Dacogen; 5-Aza-dC
Application:	DNA Methyltransferase Inhibitors
CAS Number:	2353-33-5
Formula:	C8H12N4O4
Molecular Weight:	228.2
SMILES:	C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O
*Solubility-In vitro:*	In vitro (25°C): DMSO: 44 mg/mL (192.8 mM) Water: 10 mg/mL (43.81 mM) Ethanol: Insoluble
*Solubility-In vivo:*	water: 9 mg/mL

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 43.82 mL 0.1 mM_5 mg: 219.11 mL 0.1 mM_10 mg: 438.21 mL 0.5 mM_1 mg: 8.76 mL 0.5 mM_5 mg: 43.82 mL 0.5 mM_10 mg: 87.64 mL 1 mM_1 mg: 4.38 mL 1 mM_5 mg: 21.91 mL 1 mM_10 mg: 43.82 mL 5 mM_1 mg: 0.88 mL 5 mM_5 mg: 4.38 mL 5 mM_10 mg: 8.76 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.