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Ezetimibe (Zetia)
Product Name: | Ezetimibe (Zetia) |
CAT#: | DMMRP-2312-LGZ-11 |
Package: | 25mg/100mg/(Zetia) 10mM * 1mL in DMSO |
Datasheet |
Description
Ezetimibe is a cholesterol-lowering compound. It works by reducing the absorption of cholesterol in the intestines. Ezetimibe is located at the brush border of the small intestine and inhibits the absorption of cholesterol in the small intestine.
Basic Information
Synonyms: | Zetia ; Ezetrol |
CAS Number: | 163222-33-1 |
Formula: | C24H21F2NO3 |
Molecular Weight: | 409.4 |
SMILES: | C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O |
Solubility-In vitro: | In vitro (25°C): DMSO: 75 mg/mL (183.19 mM) Water: Insoluble Ethanol: 75 mg/mL (183.19 mM) |
Solubility-In vivo: | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O: 9 mg/mL |
Storage
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Preparing Stock Solutions
0.1 mM_1 mg: 24.43 mL
0.1 mM_5 mg: 122.13 mL
0.1 mM_10 mg: 244.26 mL
0.5 mM_1 mg: 4.89 mL
0.5 mM_5 mg: 24.43 mL
0.5 mM_10 mg: 48.85 mL
1 mM_1 mg: 2.44 mL
1 mM_5 mg: 12.21 mL
1 mM_10 mg: 24.43 mL
5 mM_1 mg: 0.49 mL
5 mM_5 mg: 2.44 mL
5 mM_10 mg: 4.89 mL
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