Garcinol

Product Name:	Garcinol
CAT#:	DEHA-2312-LGZ-2
Package:	10mg/25mg/50mg/100mg
Datasheet

Description

Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a highly effective inhibitor of histone acetyltransferases (HATs) p300 with IC50 of 7μM and PCAF with IC50 of 5μM both in vitro and in vivo.

Basic Information

Synonyms:	Camboginol
Application:	HAT Inhibitor
CAS Number:	78824-30-3
Formula:	C38H50O6
Molecular Weight:	602.8
SMILES:	CC(=CC[C@@H]1C[C@@]2(C(=O)/C(=C(\C3=CC(=C(C=C3)O)O)/O)/C(=O)[C@@](C2=O)(C1(C)C)CC=C(C)C)C[C@H](CC=C(C)C)C(=C)C)C

Target Info

:	AChE
:	BChE
:	GCN5/PCAF
:	Human Endogenous Metabolite

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

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