Hesperetin

Product Name:	Hesperetin
CAT#:	DMA-2312-LGZ-7
Package:	5mg/10mg/50mg/100mg/10mM * 1mL in DMSO
Datasheet

Description

Hesperetin, a selective phosphodiesterase (PDE) 4 inhibitor, is a citrus flavonoid reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in Hep-G2 cells and reduces ApoB protein synthesis in a dose-dependent manner. It is also a highly effectiveial treatment for carcinoid tumors.

Basic Information

Application:	PDE4 Inhibitor
CAS Number:	520-33-2
Formula:	C16H14O6
Molecular Weight:	302.3
SMILES:	COC1=C(C=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)O
*Solubility-In vitro:*	DMSO: 58 mg/mL (191.87 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 33.08 mL 0.1 mM_5 mg: 165.4 mL 0.1 mM_10 mg: 330.8 mL 0.5 mM_1 mg: 6.62 mL 0.5 mM_5 mg: 33.08 mL 0.5 mM_10 mg: 66.16 mL 1 mM_1 mg: 3.31 mL 1 mM_5 mg: 16.54 mL 1 mM_10 mg: 33.08 mL 5 mM_1 mg: 0.66 mL 5 mM_5 mg: 3.31 mL 5 mM_10 mg: 6.62 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.