Inauhzin

Product Name:	Inauhzin
CAT#:	DES-2312-LGZ-8
Package:	5mg/10mg/25mg/50mg
Datasheet

Description

Inauhzin is a highly effective SIRT inhibitor that effectively reactivates p53 by inhibiting SIRT1 activity and promotes p53-dependent human tumor cell apoptosis without causing obvious genotoxic stress.

Basic Information

Application:	SIRT1 Inhibitor
CAS Number:	309271-94-1
Formula:	C25H19N5OS2
Molecular Weight:	469.58
SMILES:	CCC(C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31)SC4=NC5=C(C6=CC=CC=C6N5)N=N4
*Solubility-In vitro:*	DMSO: 82 mg/mL (174.62 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Target Info

:	SIRT1/ MDM-2/p53/ IMPDH2

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 21.3 mL 0.1 mM_5 mg: 106.48 mL 0.1 mM_10 mg: 212.96 mL 0.5 mM_1 mg: 4.26 mL 0.5 mM_5 mg: 21.3 mL 0.5 mM_10 mg: 42.59 mL 1 mM_1 mg: 2.13 mL 1 mM_5 mg: 10.65 mL 1 mM_10 mg: 21.3 mL 5 mM_1 mg: 0.43 mL 5 mM_5 mg: 2.13 mL 5 mM_10 mg: 4.26 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.