Solutions
Online Inquiry

Please note that we are not a pharmacy or clinic, so we are unable to see patients and do not offer diagnostic and treatment services for individuals.

Inquiry

JNJ-26481585 (Quisinostat)

Product Name: JNJ-26481585 (Quisinostat)
CAT#: DEH-2312-LGZ-4
Package: 5mg/10mg/50mg/100mg/10mM * 1mL in DMSO
Datasheet
875320-29-9.png

Description

JNJ-26481585, also known as Quisinostat, is a pan-HDAC inhibitor with significant potency against HDAC1 (IC(50), 0.16 nmol/L).

Basic Information

Synonyms: JNJ26481585
Application: HDAC Inhibitor
CAS Number: 875320-29-9
Formula: C21H26N6O2
Molecular Weight: 394.5
SMILES: CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO

Target Info

HDAC1: 0.11 nM (IC50)
HDAC2: 0.33 nM (IC50)
HDAC11: 0.37 nM (IC50)
HDAC10: 0.46 nM (IC50)
HDAC5: 3.69 nM (IC50)
HDAC8: 4.26 nM (IC50)
HDAC3: 4.86 nM (IC50)
HDAC9: 32.1 nM (IC50)
HDAC6: 76.8 nM (IC50)
HDAC7: 119 nM (IC50)

Storage

  • The lyophilized form should be stored at -20°C, in a desiccated environment.
  • In lyophilized form, the chemical remains stable for 36 months.
  • In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Copyright © Protheragen. All rights reserves.