MC1568

Product Name:	MC1568
CAT#:	DEH-2312-LGZ-7
Package:	10mg/25mg/50mg/100mg/10mM * 1mL in DMSO
Datasheet

Description

MC1568 is a member of histone deacetylase (HDAC) inhibitors. It inhibits histone deacetylase class II by modifying the gene expression of multiple important genes in the cell cycle, thereby causing breast cancer cell apoptosis.

Basic Information

Synonyms:	MC-1568
Application:	HDAC Inhibitor
CAS Number:	852475-26-4
Formula:	C17H15FN2O3
Molecular Weight:	314.3
SMILES:	CN1C=C(C=C1/C=C/C(=O)NO)/C=C/C(=O)C2=CC(=CC=C2)F
*Solubility-In vitro:*	In vitro (25°C): DMSO: 12 mg/mL (38.18 mM) Water: Insoluble Ethanol: Insoluble
*Solubility-In vivo:*	0.5% CMC: 4 mg/mL

Target Info

HD1-A (Maize) (Cell-free assay):	100 nM
HD1-B (Maize) (Cell-free assay):	3.4 μM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 31.82 mL 0.1 mM_5 mg: 159.08 mL 0.1 mM_10 mg: 318.17 mL 0.5 mM_1 mg: 6.36 mL 0.5 mM_5 mg: 31.82 mL 0.5 mM_10 mg: 63.63 mL 1 mM_1 mg: 3.18 mL 1 mM_5 mg: 15.91 mL 1 mM_10 mg: 31.82 mL 5 mM_1 mg: 0.64 mL 5 mM_5 mg: 3.18 mL 5 mM_10 mg: 6.36 mL

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