MG149

Product Name:	MG149
CAT#:	DEHA-2312-LGZ-5
Package:	5mg/10mg/25mg/10mM * 1mL in DMSO
Datasheet

Description

MG149 is a highly effective histone acetyltransferase inhibitor (IC50 values are 74 uM and 47 uM for Tip60 and MOF).

Basic Information

Synonyms:	MG 149,MG-149
Application:	KAT5 (Tip60) HAT Inhibitor
CAS Number:	1243583-85-8
Formula:	C22H28O3
Molecular Weight:	340.46
SMILES:	CCCCCCCC1=CC=C(C=C1)CCC2=C(C(=CC=C2)O)C(=O)O
*Solubility-In vitro:*	DMSO: 63 mg/mL (185.03 mM) Water: Insoluble Ethanol: 63 mg/mL (185.03 mM) * <1 mg/ml means slightly soluble or insoluble.

Target Info

MOF:	47 μM
Tip60:	74 μM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 29.37 mL 0.1 mM_5 mg: 146.86 mL 0.1 mM_10 mg: 293.72 mL 0.5 mM_1 mg: 5.87 mL 0.5 mM_5 mg: 29.37 mL 0.5 mM_10 mg: 58.74 mL 1 mM_1 mg: 2.94 mL 1 mM_5 mg: 14.69 mL 1 mM_10 mg: 29.37 mL 5 mM_1 mg: 0.59 mL 5 mM_5 mg: 2.94 mL 5 mM_10 mg: 5.87 mL

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