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NU 9056

Description

NU9056 is a selective KAT5 (Tip60) HAT inhibitor. IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Inhibiting protein acetylation and blocking DNA damage response in prostate cancer cell lines inhibits LNCaP cell proliferation and induces apoptosis through caspase activation.

Basic Information

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment. In lyophilized form, the chemical remains stable for 36 months. In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

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