O6-Benzylguanine

Product Name:	O6-Benzylguanine
CAT#:	DEDM-2312-LGZ-8
Package:	50mg/100mg/500mg
Datasheet

Description

O6-Benzylguanine is an effective substrate and highly efficient inactivator of DNA alkyltransferase and an inhibitor of MGMT.

Basic Information

Synonyms:	CCRIS 9383
Application:	MGMT Inhibitor
CAS Number:	19916-73-5
Formula:	C12H11N5O
Molecular Weight:	241.25
SMILES:	NC1=NC2=NC=NC2=C(OCC3=CC=CC=C3)N1
*Solubility-In vitro:*	DMSO: 41 mg/mL (169.95 mM) Water: Insoluble Ethanol: 10 mg/mL * <1 mg/ml means slightly soluble or insoluble.

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 41.45 mL 0.1 mM_5 mg: 207.25 mL 0.1 mM_10 mg: 414.51 mL 0.5 mM_1 mg: 8.29 mL 0.5 mM_5 mg: 41.45 mL 0.5 mM_10 mg: 82.9 mL 1 mM_1 mg: 4.15 mL 1 mM_5 mg: 20.73 mL 1 mM_10 mg: 41.45 mL 5 mM_1 mg: 0.83 mL 5 mM_5 mg: 4.15 mL 5 mM_10 mg: 8.29 mL

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