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O6BTG-octylglucoside

Product Name: O6BTG-octylglucoside
CAT#: DEDM-2312-LGZ-2
Package: 5mg/10mg/50mg/100mg
Datasheet
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Description

O6BTG-octylglucoside is a highly effective O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.

Basic Information

Synonyms: Glucose-conjugated MGMT inhibitor
Application: MGMT Inhibitor
CAS Number: 382607-78-5
Formula: C24H34BrN5O7S
Molecular Weight: 616.53
SMILES: [H][C@]1([C@]([H])(O[C@@](OCCCCCCCCN2C3=C(N=C2)C(OCC4=CC(Br)=CS4)=NC(N)=N3)([C@](O)([C@]1(O)[H])[H])[H])CO)O

Target Info

MGMT: 32 nM (IC50)

Storage

  • The lyophilized form should be stored at -20°C, in a desiccated environment.
  • In lyophilized form, the chemical remains stable for 36 months.
  • In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

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