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PROseq 96-Unique Dual Index

This kit includes all the necessary reagents (excluding indices) to process 12 samples for analysis of gene fusions, gene expression, and RNA SNP/InDel in RNA sequencing.

Features

The design flexibility is enhanced by the incorporation of PROseq single primer extension (SPE) chemistry. PCR duplicates are eliminated and sensitivity and specificity are maximized by unique molecular indices (UMIs). It is fully customizable. The workflow is streamlined and a single-tube enrichment pool allows for easy setup. It is an excellent solution for difficult sample types like FFPE.

Product Details

The PROseq RNA Fusion XP facilitates the simultaneous analysis of RNA fusion, gene expression and SNV from a single sample, enabling the in-depth insights required by comprehensive RNA-seq research. PROTHERAGEN utilizes its top-tier curated design content and matchless custom assay skills to offer unparalleled NGS flexibility. Most fusion detection systems have a high false-positive rate due to the demand for high sensitivity in analyses. However, PROseq Fusion XP Targeted Panels outshine all by providing an extremely low false-positive rate with high fusion detection sensitivity. By employing our SPE chemistry that necessitates merely one gene-specific primer per target, PROseq Fusion XP Targeted panels render exceptional versatility for targeting fusions and densely overlapping SNV regions of interest. Moreover, all our kits are optimized for use with unique dual index adapters. Our catalogue houses panels that target sarcoma, leukemia, lymphoma and other oncology applications. Our custom panels are fully adjustable to support both gene-level and transcript-based designs.

Applications

Fusion gene events, gene expression, and SNP/InDel at the RNA level can be identified and characterized with the help of PROseq RNA Fusion XP Panels. These panels utilize single primer extension (SPE) and unique molecular index (UMI) technologies in next-generation sequencing (NGS).

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.