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PROseq xHYB Human Custom Panel
The PROseq xHYB Custom Human Panel includes only the custom probe sets necessary for hybridization capture, plus 12 hybrid capture reactions, typically enough for 96 samples.
Features
The algorithm for custom probe design is flexible and offers excellent coverage of the target area. It can detect variants with low allele frequencies with high sensitivity. The workflow is designed in such a way that it can be completed in a single day, with the flexibility of hybrid capture that can range from 30 minutes to overnight. The workflow is designed to be automation-friendly. |
Product Details
PROTHERAGEN offers various options for customization of enriched targets: A fully custom panel: This panel is designed to focus on the customer's specific regions of interest (ROIs). Use with an existing panel: This option allows customers to combine a custom panel with either a PROseq xHYB Human Hybrid Capture Panel or another custom panel. Boosting an existing panel (unlimited ROIs): With this option, a panel is constructed to enhance ROIs with more probes, thereby increasing coverage. |
Applications
The extensive use of exome sequencing has paved the way for various, economical methods for disease-oriented research. Various applications that employ exome sequencing can use PROseq Human Exome Kits, including: Identifying disease genes for uncommon and familial diseases Studying population genetics and carrier screening Researching human disease pathways and mechanisms Investigating pathogenic infection mechanisms. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.