Recombinant Human CXADR/CAR Protein, C-6His
Description
The Coxsackievirus and Adenovirus Receptor (CAR) is a glycoprotein belonging to the CTX family of the Ig superfamily. It is expressed in various tissues including the pancreas, brain, heart, small intestine, testis, and prostate. CAR acts as a receptor for gene transfer and also functions as an adhesion molecule within junctional complexes. These complexes are particularly important between epithelial cells lining body cavities and within myocardial intercalated discs. The structure of CAR consists of an extracellular domain, a transmembrane helix, and a C-terminal intracellular domain. The C-terminal region interacts with several cytoplasmic junctional proteins, microtubules, and the actin cytoskeleton.
Basic Information
| Synonyms: | Coxsackievirus and Adenovirus Receptor, CAR, hCAR, CVB3-Binding Protein, Coxsackievirus B-Adenovirus Receptor, HCVADR, CXADR, CAR |
| Source/Host: | HEK293 Cells |
| Tag: | C-6His |
| Mol_Mass: | 25.1 kDa |
| AP_Mol_Mass: | 32 kDa |
| Uniprot: | P78310 |
| Accession: | P78310 |
| Sequence: | Leu20-Gly237 |
| Species: | Human |
Product Properties
| Endotoxin Level: | < 1.0 EU per μg (LAL method). |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Prior to lyophilization, add protectants including 5% - 8% trehalose, mannitol, and 0.01% Tween80. |
| Purity: | > 95 % (by reducing SDS-PAGE). |
Shipping and Handling
| Shipping: | Shipped with ice packs (the product is lyophilized powder). |
| Stability & Storage: | Please store lyophilized proteins at temperatures between -20 to -80°C for a maximum of 12 months. Once reconstituted, the protein solution can be stored at temperatures ranging from 4-8°C for a period of 2-7 days. If you need to store aliquots of reconstituted samples, please ensure they are kept below -20°C and they will remain stable for up to 3 months. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
