Recombinant Human MR-ProADM Protein, N-GST
Description
AM and PAMP are powerful agents that lower blood pressure and dilate blood vessels. They have various effects, most of which are related to the regulation of fluid and electrolyte balance in the body. In the kidneys, AM promotes urine production and sodium excretion, while both AM and PAMP directly inhibit the secretion of aldosterone from the adrenal glands. In the pituitary gland, both peptides suppress the release of basal ACTH at doses relevant to physiological conditions. These peptides also appear to act in the brain and pituitary gland to enhance plasma volume loss, which complements their hypotensive effects on blood vessels.
Basic Information
| Synonyms: | AM, ProAM N-terminal 20 peptide, PAMP, ProAM-N20 |
| Source/Host: | E.coli |
| Tag: | N-GST |
| Mol_Mass: | 31.3 kDa |
| AP_Mol_Mass: | 32 kDa |
| Uniprot: | P35318 |
| Accession: | P35318 |
| Sequence: | Glu45-Val92 |
| Species: | Human |
Product Properties
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Prior to lyophilization, add protectants including 5% - 8% trehalose, mannitol, and 0.01% Tween80. |
| Purity: | > 85 % (by reducing SDS-PAGE). |
Shipping and Handling
| Shipping: | Shipped with ice packs (the product is lyophilized powder). |
| Stability & Storage: | Please store lyophilized proteins at temperatures between -20 to -80°C for a maximum of 12 months. Once reconstituted, the protein solution can be stored at temperatures ranging from 4-8°C for a period of 2-7 days. If you need to store aliquots of reconstituted samples, please ensure they are kept below -20°C and they will remain stable for up to 3 months. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
