Recombinant Human SQSTM1/p62 Protein, N-His
Description
Create an adapter protein capable of binding ubiquitin and potentially controlling the activation of NFKB1 through TNF-alpha, nerve growth factor (NGF), and interleukin-1. Additionally, investigate its role in downstream signaling of titin/TTN in muscle cells. Explore its potential to regulate signaling pathways via ubiquitination. Develop an adapter that facilitates interaction between TRAF6 and CYLD (similar to existing models). Investigate its involvement in cell differentiation, apoptosis, immune response, and regulation of K(+) channels.
Basic Information
Synonyms: | A170, DMRV, EBI 3 associated protein p60, EBIAP, FTDALS3, ORCA, OSF-6, OSIL, p60, P62b, PDB 3, PDB3, Sequestosome 1, SQSTM 1, STAP, STONE14, ZIP3 |
Source/Host: | E.coli |
Tag: | N-His |
Mol_Mass: | 10.89 kDa |
AP_Mol_Mass: | 15 kDa |
Uniprot: | Q13501 |
Accession: | Q13501 |
Sequence: | Ser3-Lys102 |
Species: | Human |
Product Properties
Formulation: | Lyophilized from sterile PBS, pH 7.4. Prior to lyophilization, add protectants including 5% - 8% trehalose, mannitol, and 0.01% Tween80. |
Purity: | > 95 % (by reducing SDS-PAGE). |
Shipping and Handling
Shipping: | Shipped with ice packs (the product is lyophilized powder). |
Stability & Storage: | Please store lyophilized proteins at temperatures between -20 to -80°C for a maximum of 12 months. Once reconstituted, the protein solution can be stored at temperatures ranging from 4-8°C for a period of 2-7 days. If you need to store aliquots of reconstituted samples, please ensure they are kept below -20°C and they will remain stable for up to 3 months. |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.