RG108

Product Name:	RG108
CAT#:	DEDM-2312-LGZ-6
Package:	25mg/50mg/100mg/10mM * 1mL in DMSO
Datasheet

Description

RG108 is a non-nucleoside inhibitor of DNA methyltransferase with an IC50 value of 115 nM.

Basic Information

Synonyms:	RG 108; RG-108
Application:	DNA Methyltransferase Inhibitor
CAS Number:	48208-26-0
Formula:	C19H14N2O4
Molecular Weight:	334.33
SMILES:	C1=CC=C2C(=C1)C(=O)N(C2=O)[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O
*Solubility-In vitro:*	DMSO: 62 mg/mL (185.44 mM) Water: Insoluble Ethanol: 62 mg/mL (185.44 mM) * <1 mg/ml means slightly soluble or insoluble.

Target Info

DNA methyltransferase (Cell-free assay):

115 nM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 29.91 mL 0.1 mM_5 mg: 149.55 mL 0.1 mM_10 mg: 299.11 mL 0.5 mM_1 mg: 5.98 mL 0.5 mM_5 mg: 29.91 mL 0.5 mM_10 mg: 59.82 mL 1 mM_1 mg: 2.99 mL 1 mM_5 mg: 14.96 mL 1 mM_10 mg: 29.91 mL 5 mM_1 mg: 0.6 mL 5 mM_5 mg: 2.99 mL 5 mM_10 mg: 5.98 mL

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