Sirtuins
Sirtuins are widely distributed in cells and consist of a group of proteins, with a total of 7 subtypes SIRT1~SIRT7. The main function of sirtuins is to deacetylate proteins, an important protein modification process. Through deacetylation, sirtuins can maintain protein function and stability and participate in a variety of cellular processes.
Epigenetic and post-translational modification mechanisms have been found to control immune responses and metabolic reprogramming. Sirtuins are NAD+-dependent histone deacetylase enzymes that have recently been reported to play a potential role in immune responses. Therefore, sirtuins are of great significance as therapeutic targets for treating immune-related diseases and enhancing anti-tumor immunity.
For more details about our sirtuins, please click the links listed below.
- SirReal2
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CAT#:
DES-2312-LGZ-14
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CAS Number:
709002-46-0
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Application:
Selective SIRT2 Inhibitor
- OSS-128167
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CAT#:
DES-2312-LGZ-15
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CAS Number:
887686-02-4
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Application:
SIRT 6 Inhibitor
- Thiomyristoyl
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CAT#:
DES-2312-LGZ-17
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CAS Number:
1429749-41-6
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Application:
SIRT2 Inhibitor
- MDL-800
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CAT#:
DES-2312-LGZ-18
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CAS Number:
2275619-53-7
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Application:
SIRT6 Allosteric Activator