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Sodium Stibogluconate

Product Name: Sodium Stibogluconate
CAT#: DEPTP-2312-LGZ-7
Package: 1000mg
Datasheet
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Description

Sodium stibogluconate is a highly effective protein tyrosine phosphatase inhibitor, inhibiting 99% of SHP-1, SHP-2 and PTP1B activities at 10, 100 and 100 μ g/mL respectively.

Basic Information

Synonyms: Stibogluconate Trisodium Nonahydrate
Application: PTP Inhibitor
CAS Number: 16037-91-5
Formula: C12H38Na3O26Sb2
Molecular Weight: 910.9
SMILES: C([C@H]([C@@H]1[C@@H]([C@@H](O[Sb](O1)O[Sb]2(=O)O[C@@H]([C@@H]([C@@H](O2)C(=O)[O-])O)[C@@H](CO)O)C(=O)[O-])O)O)O.O.O.O.O.O.O.O.O.O.[OH-].[Na+].[Na+].[Na+]
Solubility-In vitro: DMSO: Insoluble
Water: 19 mg/mL (20.92 mM)
Ethanol: Insoluble
* <1 mg/ml means slightly soluble or insoluble.

Storage

  • The lyophilized form should be stored at -20°C, in a desiccated environment.
  • In lyophilized form, the chemical remains stable for 36 months.
  • In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 10.98 mL 0.1 mM_5 mg: 54.89 mL 0.1 mM_10 mg: 109.78 mL 0.5 mM_1 mg: 2.2 mL 0.5 mM_5 mg: 10.98 mL 0.5 mM_10 mg: 21.96 mL 1 mM_1 mg: 1.1 mL 1 mM_5 mg: 5.49 mL 1 mM_10 mg: 10.98 mL 5 mM_1 mg: 0.22 mL 5 mM_5 mg: 1.1 mL 5 mM_10 mg: 2.2 mL

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