SRT1720 HCl

Product Name:	SRT1720 HCl
CAT#:	DES-2312-LGZ-3
Package:	5mg/10mg/50mg/200mg/10mM * 1mL in DMSO
Datasheet

Description

SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.

Basic Information

Synonyms:	SRT-1720
Application:	SIRT1 Activator
CAS Number:	1001645-58-4
Formula:	C25H23N7OS.HCl
Molecular Weight:	506
SMILES:	C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl
*Solubility-In vitro:*	DMSO: 34 mg/mL (67.19 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Target Info

SIRT1 (Cell-free assay):

0.16 μM(EC50)

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 19.76 mL 0.1 mM_5 mg: 98.81 mL 0.1 mM_10 mg: 197.63 mL 0.5 mM_1 mg: 3.95 mL 0.5 mM_5 mg: 19.76 mL 0.5 mM_10 mg: 39.53 mL 1 mM_1 mg: 1.98 mL 1 mM_5 mg: 9.88 mL 1 mM_10 mg: 19.76 mL 5 mM_1 mg: 0.4 mL 5 mM_5 mg: 1.98 mL 5 mM_10 mg: 3.95 mL

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