StemRegenin 1 (SR1)

Product Name:	StemRegenin 1 (SR1)
CAT#:	DMAR-2312-LGZ-3
Package:	10mg/25mg/50mg/100mg/10mM * 1mL in DMSO
Datasheet

Description

StemRegenin 1, also known as SR1, is a cell-permeable purine derivative that acts as an antagonist of the aryl hydrocarbon receptor to promote self-renewal of hematopoietic stem cells (HSCs).

Basic Information

Synonyms:	SR-1
Application:	AhR AntAgonist
CAS Number:	1227633-49-9
Formula:	C24H23N5OS
Molecular Weight:	429.5
SMILES:	CC(C)N1C=NC2=C1N=C(N=C2NCCC3=CC=C(C=C3)O)C4=CSC5=CC=CC=C54
*Solubility-In vitro:*	DMSO: 84 mg/mL (195.55 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Target Info

Aryl hydrocarbon receptor (AhR) ():

127 nM

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 23.28 mL 0.1 mM_5 mg: 116.41 mL 0.1 mM_10 mg: 232.83 mL 0.5 mM_1 mg: 4.66 mL 0.5 mM_5 mg: 23.28 mL 0.5 mM_10 mg: 46.57 mL 1 mM_1 mg: 2.33 mL 1 mM_5 mg: 11.64 mL 1 mM_10 mg: 23.28 mL 5 mM_1 mg: 0.47 mL 5 mM_5 mg: 2.33 mL 5 mM_10 mg: 4.66 mL

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.